郭瑛瑛

  • 职 称:副研究员
  • 性 别:
  • 电 话:
  • 学 历:博士研究生
  • Email:yyguo@rcees.ac.cn
  • 地 址:北京海淀区双清路18号
  • 邮 编:100085

简历

教育经历

2009/09-2015/07 清华大学 生命科学学院 生物化学与分子生物学,博士 导师:陈国强

2005/09-2009/07 山东大学 生命科学学院 理学学士


工作经历

2018/07-至今,中国科学院生态环境研究中心,环境化学与生态毒理学国家重点实验室,助理研究员

2009/09-2015/07 清华大学 生命科学学院 生物化学与分子生物学, 博士后, 合作导师: 陈国强


研究领域

环境化学,环境微生物学


研究方向

重金属的微生物转化


承担科研项目情况

国家自然科学基金委员会, 面上项目, 42277208, 水环境中颗粒结合态二价汞的微生物有效性与甲基化研究, 2023-01-01 至 2026-12-31, 54万元, 在研, 参与

国家自然科学基金委员会, 青年科学基金项目, 21906168, 硫化汞纳米颗粒的微生物摄入及其在汞甲基化过程中的作用研究, 2020-01-01 至 2022-12-31, 26万元, 结题, 主持

国家科技部, 国家重点研发计划, 2020YFA0907502, 新型污染物生物感知元器件设计优化与感知生物体系构建, 2020-11 至 2024-10, 484万元, 在研, 参与


代表论著

Yingying Guo, Yuping Xiang, Guangliang Liu, Ying Chen, Yanwei Liu, Maoyong Song, Yanbin Li, Jianbo Shi, Ligang Hu, Yongguang Yin, Yong Cai, Guibin Jiang. “Trojan Horse” Type Internalization Increase the Bioavailability of Mercury Sulfide Nanoparticles and Methylation after Intracellular Dissolution. ACS Nano, 2023, 17: 1925-1934.

Qingqing Yang, Yingying Guo, Yuping Xiang, Lufeng Chen, Guangliang Liu, Yanwei Liu, Jianbo Shi, Ligang Hu, Yong Liang, Yongguang Yin, Yong Cai, Guibin Jiang. Toward Efficient Bioremediation of Methylmercury in Sediment Using merB Overexpressed Escherichia coli. Water Research, 2023, 229:119502.

Yuping Xiang, Yingying Guo, Guangliang Liu, Yanwei Liu, Maoyong Song, Jianbo Shi, Ligang Hu, Yongguang Yin, Yong Cai, Guibin Jiang. Particle-Bound Hg(II) is Available for Microbial Uptake as Revealed by a Whole-Cell Biosensor, Environmental Science & Technology, 2022, 56(10):6754-6764.

Xiaoyan Zhang, Yingying Guo, Guangliang Liu, Yanwei Liu, Maoyong Song, Jianbo Shi, Ligang Hu, Yanbin Li, Yongguang Yin, Yong Cai; Guibin Jiang. Dark Reduction of Mercury by Microalgae-Associated Aerobic Bacteria in Marine Environments, Environmental Science & Technology, 2021,55(20): 14258-14268

Pengfei Ouyang#, Huan Wang, Iivan Hajnal, Yingying Guo*, Chen GQ*, Increasing Oxygen Availability for Improving Poly(3-hydroxybutyrate) Production by Halomonas, Metabolic Engineering, 2018, 45: 20-31

Qin Qin#, Chen Ling, Yiqing Zhao, Tian Yang, Jin Yin, Yingying Guo*, Chen GQ*, CRISPR/Cas9 Editing Genome of Extremophile Halomonas spp, Metabolic Engineering, 2018, 47:219-229.

Xiang Ao#, Yi Yao, Tian Li, Tingting Yang, Xu Dong, Zetong Zheng, Guoqing Chen, Qiong Wu *, Yingying Guo*, A Multiplex Genome Editing Method for Escherichia coli Based on CRISPR-Cas12a, Frontiers in Microbiology, 2018, 9:2307.

Chen Ling#, Guanqing Qiao, Bowen Shuai, Karl Olavariia, Jin Yin, Ruijuan Xiang, Kunnan Song, Yunhao Shen, Yingying Guo*, Guoqiang Chen*, Engineering NADH/NAD+ Ratio in Halomonas bluephagenesis forEnhanced Production of Polyhydroxyalkanoates (PHA), Metabolic Engineering, 2018, 49:275-286.

Shaoqin Zhang#, Lei Fang, Zhengjun Li, Qiong Wu, Yingying Guo*, Guoqiang Chen*, Enhanced Production of Poly-3-hydroxybutyrate by Recombinant Escherichia coli Containing NAD Kinase and phbCAB Operon, A Special Issue on “Bio-based and biodegradable polymers” to Science China Chemistry, 2016, 59: 1390-1396.

Tian Li#, Yingying Guo#, Guanqing Qiao, Qiong Wu, Guoqinag Chen*, Microbial Synthesis of 5-Aminolevulinic Acid (ALA) and Its Co-production with Polyhydroxybutyrate (PHB), ACS Synthetic Biology, 2016, 5 :1264-1274.

Yingying Guo#, Zhengyu Shi, Xiaozhi Fu, Jinchun Chen, Qiong Wu, Guoqinag Chen*, A Strategy for Enhanced Circular DNA Construction Efficiency based on DNA Cyclization after Microbial Transformation, Microbiology Cell Factory, 2015, 14:18.